SODIUM CARBOXYMETHYL CELLULOSE POVIDONE-IODE IN DILUTED SOLUTIONS THERMODYNAMICS OF VOLATILE WITH

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Published: 09.06.2025
DOI: https://doi.org/10.70769/3030-3214.SRT.3.2.2025.31
Keywords:
iodine complex of polyvinylpyrrolidone, sodium carboxymethylcellulose (Na-CMC), surface-active substance (SAM), surface tension, PVJ-N-methylene

Main Article Content

Zokirova, N.T.
Кандидат химических наук, доцент, Ташкентский фармацевтический институт, Ташкент, Узбекистан , Kimyo fanlari nomzodi, dotsent, Tashkent farmatsevtika instituti, Toshkent, O‘zbekiston , Candidate of Chemical Sciences, Associate Professor, Tashkent Pharmaceutical Institute, Tashkent, Uzbekistan
https://orcid.org/0000-0002-8405-3147 (unauthenticated)
Muhamedova, B.I.
Кандидат фармацевтических наук, доцент, Ташкентский фармацевтический институт, Ташкент, Узбекистан , Farmatsiya fanlari nomzodi, dotsent, Tashkent farmatsevtika instituti, Toshkent, O‘zbekiston , Candidate of Pharmaceutical Sciences, Associate Professor, Tashkent Pharmaceutical Institute, Tashkent, Uzbekistan
https://orcid.org/0000-0001-5337-2279 (unauthenticated)
Todjiyev, J.N.
Доктор философии по химии, доцент, Национальный университет Узбекистана имени Мирзо Улугбека, Ташкент, Узбекистан , Kimyo fanlari bo’yicha falsafa doktori, dotsent, Mirzo Ulug’bek nomidagi Oʻzbekiston Milliy universiteti, Toshkent, O‘zbekiston , Doctor of Philosophy in Chemistry, Associate Professor, Mirzo Ulugbek National University of Uzbekistan, Tashkent, Uzbekistan
https://orcid.org/0000-0001-5932-3849 (unauthenticated)

Abstract

This article investigates the thermodynamic properties of the interaction between sodium carboxymethyl cellulose (Na-CMC) and povidone-iodine in diluted aqueous solutions. The formation of interpolyelectrolyte complexes was analyzed using UV-VIS spectrophotometry, conductivity, pH measurements, and potentiometric titration methods. The strongest interaction was observed at a Na-CMC/povidone-iodine ratio of 1.5:1. Thermodynamic parameters such as Gibbs free energy, ionization, and conformational transitions were calculated. Surface activity was assessed via surface tension and adsorption isotherms. FTIR spectroscopy confirmed the formation of new chemical bonds through changes in functional group vibrations. The findings have practical implications in pharmaceutical sciences, particularly for designing drug delivery systems and polymeric formulations.

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Article Details

Issue

Vol. 3 No. 2 (2025)

Section

Chemical Technology and Construction
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How to Cite

Zokirova , N. T., Muhamedova , B. I., & Todjiyev , J. N. (2025). SODIUM CARBOXYMETHYL CELLULOSE POVIDONE-IODE IN DILUTED SOLUTIONS THERMODYNAMICS OF VOLATILE WITH. Digital Technologies in Industry, 3(2), 171-176. https://doi.org/10.70769/3030-3214.SRT.3.2.2025.31

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